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    Nucleic Acids Res. 1985 Dec 9;13(23):8463-75.

    The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene.

    Burkholder AC, Hartwell LH.

    The STE2 gene of the yeast Saccharomyces cerevisiae encodes a component of the receptor for the oligopeptide pheromone alpha-factor. We have cloned and determined the nucleotide sequence of the STE2 gene. A sequence involved in the control of cell-type expression of the STE2 gene was found 5' of an open reading frame that could encode a protein of 431 amino acids. The predicted STE2 protein contains seven hydrophobic segments, suggesting that the alpha-factor receptor is an integral membrane protein. No extensive homology at the primary sequence level was detected between the predicted STE2 protein and other available protein sequences.

    PMID: 3001640 [PubMed - indexed for MEDLINE]

    PMCID: 322145

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