The structural gene for aldolase B (ALDB) maps to ...[Ann Hum Genet. 1985]

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1: Ann Hum Genet. 1985 Jul;49(Pt 3):173-80.Links

The structural gene for aldolase B (ALDB) maps to 9q13----32.

Henry I, Gallano P, Besmond C, Weil D, Mattei MG, Turleau C, Boué J, Kahn A, Junien C.

We used a cloned cDNA probe for the B subunit of human aldolase (ALDB) and Southern blotting techniques to analyse DNA from a series of rodent X human somatic cell hybrids for the presence of specific ALDB-related sequences. Our results provide evidence for the assignment of the gene for ALDB to chromosome 9. Moreover, by direct gene dosage determination in two patients with chromosome 9 unbalanced rearrangements and by in situ hybridization we refined the regional chromosomal assignment to 9q13----q32 and most probably to 9q21.3----9q22.2.

PMID: 3000275 [PubMed - indexed for MEDLINE]

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