Therapeutic equivalence of two formulations of calcipotriol-betamethasone ointment: a multicentre, randomized, double-blind study in adult patients with chronic plaque psoriasis

Br J Dermatol. 2018 Nov;179(5):1189-1191. doi: 10.1111/bjd.16913. Epub 2018 Aug 16.

Authors

N Habjanic¹, R Koytchev², R Yankova³, M Kerec-Kos⁴, D Grabnar-Peklar¹

Affiliations

¹ Clinical Development, Sandoz Development Center, Lek Pharmaceuticals d.d., Verovškova 57, 1526, Ljubljana, Slovenia.
² CCDRD AG, Hoppegarten, Germany.
³ Diagnostic and Consultation Center 'Sveti Georgi', Plovdiv, Bulgaria.
⁴ Chair of Biopharmaceutics and Pharmacokinetics, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.

PMID: 29945295
DOI: 10.1111/bjd.16913

No abstract available

Publication types

Equivalence Trial
Letter
Multicenter Study
Randomized Controlled Trial

MeSH terms

Administration, Cutaneous
Adult
Betamethasone / administration & dosage
Betamethasone / adverse effects
Betamethasone / analogs & derivatives*
Calcitriol / administration & dosage
Calcitriol / adverse effects
Calcitriol / analogs & derivatives*
Double-Blind Method
Drug Combinations
Drugs, Generic / administration & dosage*
Drugs, Generic / adverse effects
Female
Humans
Male
Middle Aged
Ointments
Psoriasis / diagnosis
Psoriasis / drug therapy*
Severity of Illness Index
Treatment Outcome

Substances

Drug Combinations
Drugs, Generic
Ointments
betamethasone dipropionate, calcipotriol drug combination
Betamethasone
Calcitriol