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Neurology. 1985 Oct;35(10):1466-8.

Sensory neuropathy with low-dose pyridoxine.

Abstract

We describe 16 patients with neuropathy associated with pyridoxine abuse. The clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g/d, and duration of consumption before symptoms was inversely proportional to the daily intake. In all patients with adequate follow-up, improvement followed discontinuation of pyridoxine. The ready availability of up to 1-gram tablets makes it likely that this neuropathy will continue to be seen.

PMID:
2993949
[PubMed - indexed for MEDLINE]
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