Graves' disease presenting as severe postpartum pruritus

BMJ Case Rep. 2018 Jun 15:2018:bcr2018225347. doi: 10.1136/bcr-2018-225347.

Abstract

A 39-year-old multigravida woman presented 3 weeks postpartum with worsening generalised pruritus without primary rash. Workup was significant for cholestasis and undiagnosed Graves' disease. She began to have symptomatic relief after starting methimazole, and liver function tests normalised as she became euthyroid.

Keywords: general practice / family medicine; hyperthyroidism; liver disease; thyroid disease; thyroiditis.

Publication types

  • Case Reports

MeSH terms

  • Antithyroid Agents / therapeutic use*
  • Female
  • Graves Disease / diagnosis*
  • Graves Disease / drug therapy
  • Graves Disease / physiopathology
  • Humans
  • Liver Function Tests
  • Methimazole / therapeutic use*
  • Postpartum Period
  • Pruritus / drug therapy
  • Pruritus / etiology*
  • Pruritus / physiopathology
  • Treatment Outcome
  • Young Adult

Substances

  • Antithyroid Agents
  • Methimazole