The Epidemiology and Management of Lung Diseases in Sickle Cell Disease: Lessons Learned from Acute and Chronic Lung Disease in Cystic Fibrosis

Shaina M Willen; Michael R DeBaun

doi:10.1016/j.pcl.2018.01.007

The Epidemiology and Management of Lung Diseases in Sickle Cell Disease: Lessons Learned from Acute and Chronic Lung Disease in Cystic Fibrosis

Pediatr Clin North Am. 2018 Jun;65(3):481-493. doi: 10.1016/j.pcl.2018.01.007.

Authors

Shaina M Willen¹, Michael R DeBaun²

Affiliations

¹ Department of Pediatrics, Division of Hematology/Oncology, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, TN, USA.
² Department of Pediatrics, Division of Hematology/Oncology, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: m.debaun@vanderbilt.edu.

PMID: 29803278
DOI: 10.1016/j.pcl.2018.01.007

Abstract

Although sickle cell disease and cystic fibrosis are two of the most common monogenic diseases presenting in childhood worldwide, cystic fibrosis and sickle cell disease enjoy vastly different funding and collaborative research efforts. Pulmonary complications in cystic fibrosis have well established guidelines and multidisciplinary involvement focusing on comorbidities, routine monitoring, infectious complications, nutrition, and treatment recommendations. These guidelines can provide a framework on which to build knowledge of lung disease in sickle cell disease.

Keywords: Cystic fibrosis; Lung disease; Sickle cell disease.

Publication types

Review

MeSH terms

Acute Disease
Anemia, Sickle Cell / complications*
Anemia, Sickle Cell / therapy
Chronic Disease
Cystic Fibrosis / complications*
Cystic Fibrosis / therapy
Humans
Lung Diseases / diagnosis
Lung Diseases / epidemiology*
Lung Diseases / therapy*