[The characteristic of vestibular ocular reflex in patients with vestibular migraine]

Objective:Analysis of vestibular ocular reflex (VOR) in patients with vestibular migraine (VM) by vestibular autorotation test (VAT). To explore the clinical value of VAT technology in the diagnosis of vestibular migraine.Method:Sixty-nine patients with VM, 73 patients with posterior circulation (PCI) vertigo and 65 normal people were examined by VAT test. The characteristics of vestibular ocular reflex were analyzed by using VAT gain, phase and asymmetry among them.Result:①Among the 69 cases of VM patients,54 cases (78.3%) were horizontal or vertical gain abnormalities, 66 cases (95.7%) were horizontal or/and vertical phase delay, and 13 cases (18.8%) were asymmetric abnormalities. ②Among the 54 (78.3%) cases of abnormal gain, 46 (66.7%) cases demonstrated high gain, 42 had high gain combined with high phase, and 36 cases were simple horizontal high gain (and mainly concentrated at 2-4 Hz, 26 cases), 8 cases (11.6%) showed low gain. ③VAT characteristics in PCI group:47 cases (64.4%) were high gain, and 11 cases (15.1%) were low gain. There was no significant difference in high gain and low gain between PCI group and VM group (χ² was 0.07 and 0.37, P>0.05). Both VM group and PCI group are high-gain, but there was significant difference in the phase delay and asymmetric indicators. ④VAT characteristics in normal people group: The four indices have low abnormally positive rates. There were statistically significant differences of the high gain and the low gain between the normal people group and VM group(χ² were 56.17 and 97.57, P<0.01).Conclusion:The vestibular ocular reflex of VM is high-gain based and was mostly in the 2-4 Hz frequency,and accompanied by phase delay. Vestibular central system was mainly involved in VM. VAT detection can provide a clue for VM diagnostics.