Format

Send to:

Choose Destination
See comment in PubMed Commons below
Oral Surg Oral Med Oral Pathol. 1988 Jan;65(1):41-4.

Disturbances in dental development after total body irradiation in bone marrow transplant recipients.

Author information

  • 1Department of Pedodontics, Huddinge Hospital, Karolinska Institute, Stockholm, Sweden.

Abstract

The dental status of 16 children who had been treated with bone marrow transplantation (BMT) for serious bone marrow diseases was followed for up to 6 years. Several types of disturbances in dental development were observed in children who had been conditioned with total body irradiation (TBI) at 10 Gy before BMT. Thus, impaired root development that caused short V-shaped roots was found in all patients, a complete failure of root development and premature apical closure were found in five patients, enamel hypoplasia was observed in four patients, and microdontia was observed in three patients conditioned with TBI. Patients younger than 6 years of age at BMT exhibited the most severe and extensive dental aberrations. The TBI at 10 Gy appeared to be the major cause of the disturbances found.

PMID:
2963247
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk