U-shaped dietary sodium-associated incidence of chronic kidney disease cautions against salt overrestriction in hypertension

Kidney Int. 2018 Apr;93(4):776-778. doi: 10.1016/j.kint.2017.11.027.

Abstract

In this population study salt intake is not associated with development of chronic kidney disease (CKD) in individuals with normal blood pressure, whereas in hypertensive individuals both low and high salt intakes are associated with increased incidence of CKD, similar to U-shaped associations between salt intake and mortality found in previous studies. The results contribute to the skepticism, which has questioned the present public health policy to reduce salt intake below 5.8 g.

Publication types

  • Comment

MeSH terms

  • Blood Pressure
  • Humans
  • Hypertension
  • Incidence
  • Renal Insufficiency, Chronic
  • Sodium Chloride, Dietary*
  • Sodium, Dietary*

Substances

  • Sodium Chloride, Dietary
  • Sodium, Dietary