Abstract
Angiosarcoma is an exceedingly rare and aggressive neoplasm. Owing to early metastasis even in low-grade tumors, it is associated with poor survival. We report a late development of an angiosarcoma in a saphenous vein graft after a femoral artery to above-knee popliteal artery bypass performed for disabling claudication. Chronic inflammation, lymphatic disruption, and thrombosis of the graft may have contributed to the malignant transformation, similar to cases described as occurring after arteriovenous fistulae creation. This case illustrates that angiosarcoma may be a rare, late complication of autogenous vascular bypass.
Copyright © 2018 Elsevier Inc. All rights reserved.
MeSH terms
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Aged
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Biopsy
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Cell Transformation, Neoplastic
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Computed Tomography Angiography
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Disease Progression
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Fatal Outcome
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Femoral Artery / diagnostic imaging
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Femoral Artery / surgery*
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Hemangiosarcoma / diagnostic imaging
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Hemangiosarcoma / etiology*
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Hemangiosarcoma / pathology
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Hemangiosarcoma / therapy
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Humans
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Male
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Peripheral Arterial Disease / diagnostic imaging
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Peripheral Arterial Disease / surgery*
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Popliteal Artery / diagnostic imaging
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Popliteal Artery / surgery*
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Saphenous Vein / pathology
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Saphenous Vein / transplantation*
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Treatment Outcome
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Vascular Grafting / adverse effects*
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Vascular Neoplasms / diagnostic imaging
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Vascular Neoplasms / etiology*
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Vascular Neoplasms / pathology
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Vascular Neoplasms / therapy