Influence of hypoxia on the metabolism and biliary excretion of trimetrexate by the isolated perfused rat liver

Biochem Pharmacol. 1986 Dec 15;35(24):4587-9. doi: 10.1016/0006-2952(86)90786-0.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Bile / metabolism*
  • Half-Life
  • Hypoxia / metabolism*
  • In Vitro Techniques
  • Kinetics
  • Liver / metabolism*
  • Male
  • Perfusion
  • Quinazolines / metabolism*
  • Rats
  • Rats, Inbred Strains
  • Trimetrexate

Substances

  • Quinazolines
  • Trimetrexate