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In our first comparative study from 1981/82 on the local therapy of rosacea with imidazole derivates (2) bifonazole cream showed the better results. Since this time we collected experiences with other 87 rosacea patients on this therapy and its variations. We divided these patients into three groups: a) rosacea teleangiektatica, b) rosacea papulopustulosa, c) rosacea ekzematosa. The therapeutical results with 0.1-0.5% bifonazole cream diluted in Ungt. emulsific. aquos., with the 1% bifonazole cream and with the combined bifonazole-metronidazole therapy are reported. Without several of the patients with rosacea ekzematosa we had moderate to excellent results with a long time intervall therapy.
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