Am J Hum Genet. 1979 Nov;31(6):680-96.

A maximum likelihood map of chromosome 1.

Rao DC, Keats BJ, Lalouel JM, Morton NE, Yee S.

Abstract

Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.

PMID:: 293128; [PubMed - indexed for MEDLINE]
PMCID:: PMC1686048

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Research Support, U.S. Gov't, P.H.S.

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Genetic Markers

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