The Clinical Applications of Endometrial Mesenchymal Stem Cells

Biopreserv Biobank. 2018 Apr;16(2):158-164. doi: 10.1089/bio.2017.0057. Epub 2017 Dec 21.

Abstract

Endometrial mesenchymal stem cells (enMSCs) are a class of novel adult stem cells with self-renewal capacity, differentiation potential, low immunogenicity, low tumorigenicity, and other biological characteristics. Since the discovery of enMSCs, they have become a hot research topic. In recent years, research on enMSC isolation and application have made great progress. In this review, we focus on the clinical applications of this cell type. The latest research on the applications of enMSCs in the immune, gynecological, cardiovascular, digestive, nervous systems and metabolic diseases, as well as biobanking of enMSCs will be reviewed.

Keywords: animal model; biobanking; biological characteristics; clinical application; endometrial mesenchymal stem cells.

Publication types

  • Review

MeSH terms

  • Adult Stem Cells* / cytology
  • Adult Stem Cells* / metabolism
  • Adult Stem Cells* / transplantation
  • Animals
  • Endometrium* / cytology
  • Endometrium* / metabolism
  • Female
  • Humans
  • Mesenchymal Stem Cell Transplantation*
  • Mesenchymal Stem Cells* / cytology
  • Mesenchymal Stem Cells* / metabolism