Constant attack on T cell lymphomas

Sci Immunol. 2017 Dec 1;2(18):eaar5171. doi: 10.1126/sciimmunol.aar5171.

Author

Gabriel K Griffin¹

Affiliation

¹ Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA. Email: gkgriffin@bwh.harvard.edu.

PMID: 29196452
DOI: 10.1126/sciimmunol.aar5171

Abstract

A proof-of-principle study generates CAR-T cells against T cell lymphoma by selectively targeting the T cell receptor β-chain constant region 1.

Copyright © 2017, American Association for the Advancement of Science.

Publication types

Letter
Comment

MeSH terms

Cell- and Tissue-Based Therapy*
Genetic Engineering
Humans
Lymphoma, T-Cell / immunology*
Lymphoma, T-Cell / therapy*