Cancer. 1989 Feb 15;63(4):807-11.

Dedifferentiated parosteal osteosarcoma of the femur with aneuploidy and lung metastases.

van Oven MW, Molenaar WM, Freling NJ, Schraffordt Koops H, Muis N, Dam-Meiring A, Oosterhuis JW.

Source

Department of Pathology, University Hospital of Groningen, The Netherlands.

Abstract

In this report, the pathologic findings and the results of cellular DNA measurements of a tumor that on first presentation seemed to be a classical parosteal osteosarcoma are described. After resection 8 months later, part of the tumor appeared to display highly malignant features. DNA flow cytometry of this part of the tumor showed an aneuploid cell population. The aggressive nature of the tumor was confirmed by the development of lung metastases approximately 1 year after resection of the primary tumor.

PMID:: 2914286; [PubMed - indexed for MEDLINE]

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DNA, Neoplasm

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Dedifferentiated parosteal osteosarcoma of the femur with aneuploidy and lung metastases.

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