Oxygen Desaturation in Daily Life and During a Laboratory-Based Protocol of Activities of Daily Living in COPD: Is There Relationship?

Lung. 2018 Feb;196(1):19-26. doi: 10.1007/s00408-017-0068-4. Epub 2017 Nov 13.

Abstract

Purpose: To analyze the relationship between oxygen desaturation episodes during a laboratory-based ADL protocol and in real-life routine in patients with stable chronic obstructive pulmonary disease (COPD).

Methods: Twenty patients with stable COPD (12 men, 70 ± 7 years, FEV1% 54 ± 15 predicted) with no indication for long-term oxygen therapy (LTOT) were submitted to assessments including ADL performance by the Londrina ADL Protocol (LAP) and level of physical activity in daily life, both while submitted to simultaneous activity and pulse oximeter monitoring.

Results: Episodes of desaturation ≥ 4% (ED ≥ 4%) during the LAP were correlated both with ED ≥ 4% in daily life (r = 0.45) and number of episodes of SpO2 under 88% (ED < 88%) in daily life (r = 0.59). ED < 88% during the LAP was also correlated with ED < 88% in daily life (r = 0.51), explaining 43% of its variance.

Conclusion: In stable patients with COPD and no indication of LTOT, episodes of desaturation during a lab-based ADL protocol are moderately related to episodes of desaturation in daily (real) life, especially those episodes under 88%.

Keywords: Activities of daily living; Chronic obstructive pulmonary disease; Motor activity; Pulse oximetry.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accelerometry
  • Activities of Daily Living*
  • Aged
  • Cross-Sectional Studies
  • Dyspnea / etiology
  • Exercise / physiology
  • Exercise Tolerance
  • Fatigue / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Oximetry
  • Oxygen / blood*
  • Pulmonary Disease, Chronic Obstructive / complications
  • Pulmonary Disease, Chronic Obstructive / physiopathology*
  • Surveys and Questionnaires
  • Walk Test

Substances

  • Oxygen