A Randomized, Controlled, Multicenter Study of Technology-Based Weight Loss Interventions among Endometrial Cancer Survivors

Obesity (Silver Spring). 2017 Nov;25 Suppl 2(Suppl 2):S102-S108. doi: 10.1002/oby.22021.

Abstract

Objective: The aim of this study was to test the efficacy of technology-based weight loss interventions for endometrial cancer (EC) survivors with obesity.

Methods: EC survivors with obesity (n = 196) from three medical centers completed assessments for knowledge of obesity as a risk for EC and interest in weight management. Forty-one women were randomized to a 6-month intervention: telemedicine with Wi-Fi scales, text messaging (texting), or enhanced usual care (EUC). Changes in anthropometrics and psychosocial measures were analyzed.

Results: One-third of survey participants lacked awareness that obesity increased the risk of EC, and 40% misclassified their body mass. There were no significant differences in weight loss across interventions (mean = -4.4 kg, SD = 6.5 kg). Telemedicine showed improvements in physical health and cancer-related body image (Ps = 0.04) compared to texting and in sexual functioning compared to EUC (P = 0.03). Total physical activity was increased in EUC compared with telemedicine (P = 0.01), and vigorous physical activity was increased in EUC compared with both interventions (P = 0.01-0.03); walking significantly increased in texting compared with telemedicine (P = 0.02).

Conclusions: Technology-based lifestyle interventions in EC survivors with obesity were accessible and resulted in weight loss and improved quality of life. EUC also produced weight loss, demonstrating a potential for beginning weight management with information on specific diet and exercise goals.

Trial registration: ClinicalTrials.gov NCT02466061.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Cancer Survivors / psychology*
  • Endometrial Neoplasms / complications
  • Endometrial Neoplasms / psychology*
  • Exercise
  • Female
  • Humans
  • Life Style
  • Middle Aged
  • Obesity / complications
  • Obesity / psychology*
  • Quality of Life*
  • Telemedicine*
  • Treatment Outcome
  • United States
  • Weight Loss*

Associated data

  • ClinicalTrials.gov/NCT02466061