Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells

Chem Commun (Camb). 2017 Oct 31;53(87):11937-11940. doi: 10.1039/c7cc07666e.

Abstract

Supramolecular self-assembly between perylenediimide-based glycoclusters and a red-emitting fluorophore produces structurally uniform and stable glyco-dots amenable to targeted fluorogenic imaging of liver and triple-negative breast cancer cells.

MeSH terms

  • Cell Line, Tumor
  • Fluorescent Dyes / chemistry*
  • Humans
  • Imides / chemistry*
  • Liver Neoplasms / diagnostic imaging*
  • Optical Imaging / methods*
  • Perylene / analogs & derivatives*
  • Perylene / chemistry
  • Triple Negative Breast Neoplasms / diagnostic imaging*

Substances

  • Fluorescent Dyes
  • Imides
  • perylenediimide
  • Perylene