Send to

Choose Destination
See comment in PubMed Commons below
Brain Res. 1988 Oct 4;461(2):393-6.

Transient increased density of NMDA binding sites in the developing rat hippocampus.

Author information

  • 1Laboratoire de Neurobiologie et Physiopathologie du Développement, INSERM U29, Paris, France.


Using quantitative autoradiography and membrane preparations, the density of specific glutamate and N-methyl-D-aspartic acid (NMDA) binding sites have been determined in the developing rat hippocampus. We found an abrupt reduction in the density of NMDA binding sites after P8 (postnatal day) without change in affinity. The transient expression of NMDA receptors during maturation suggests that they may play a particularly important role in synaptogenesis.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk