Recent experimental and computational work revealed that transcriptional terminators in Saccharomyces cerevisiae can terminate transcription coming from both directions. This mechanism helps budding yeast cope with the pervasive nature of transcription by limiting aberrant transcription from invading neighboring genes.
Keywords: Bidirectional terminators; Cryptic transcription; Hrp1; Pervasive transcription; Saccharomyces cerevisiae; Transcription.