Lung cancer is a common malignant tumor in clinic. Morbidity and mortality are the first place in cancer, which seriously threaten the health of human beings. Due to the lack of effective and specific screening methods, most patients were found already at an advanced stage, and often combined with bone, brain, liver, adrenal and other parts of the metastasis. Symptoms of patient resulted from the primary tumor, metastatic spread, or paraneoplastic syndrome commonly cause the medical attention. For the syndrome related to the distant metastatic spread as the first manifestation, diagnosis would be a challenge. Retinal metastasis is very rare as the first symptom of squamous cell carcinoma of the lung. This paper reviewed a case, in which a patient developed the retinal metastasis as the inital presentation. After systemic evaluation, our patient was managed in multidisciplinary treatments, including surgery and chemotherapy. Now, the patient has a good short-term prognosis and is still in fellow-up condition. Later, we summarized the characteristics of the diagnosis and treatment of this case and provided experience for clinicians. At the same time, reviewing the relevant literature on tumor metastasis provides a window for our understanding of the rare manifestations of lung cancer.
肺癌是临床上常见的恶性肿瘤，发病率和死亡率居肿瘤首位，严重威胁人类的健康。由于早期缺乏有效的、特异性强的筛查方法，多数患者发现时已处于中晚期，常合并骨、脑、肝、肾上腺等部位的转移。通常，患者多因原发病灶、扩散转移或副肿瘤综合征等引起临床症状而就诊。对由于远处转移相关症状作为首发表现就诊的患者，诊断是一个非常大的挑战。视网膜转移作为肺鳞癌的首发症状极其罕见。本文回顾性分析了我院收治的一例肺鳞癌患者的诊治经过，以眼部症状为首发表现，基于临床表现、影像学检查和手术病理诊断，给予患者手术、化疗等多学科综合治疗，目前短期预后良好，随访观察中。我们总结了本病例诊疗过程的特点，为临床医生提供经验。同时复习肿瘤眼内转移的相关文献，为我们对于肺癌罕见表现的深入了解提供了一个窗口。.