Modulating the Modulator: Regulation of Protein Methylation by Nitric Oxide

Lucas Frungillo; Steven H Spoel

doi:10.1016/j.molcel.2017.08.001

Modulating the Modulator: Regulation of Protein Methylation by Nitric Oxide

Mol Cell. 2017 Aug 17;67(4):535-537. doi: 10.1016/j.molcel.2017.08.001.

Authors

Lucas Frungillo¹, Steven H Spoel²

Affiliations

¹ Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
² Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK. Electronic address: steven.spoel@ed.ac.uk.

PMID: 28820964
DOI: 10.1016/j.molcel.2017.08.001

Abstract

Protein methylation is an important modulator of signal transduction pathways, but methyltransferases themselves may also be modulated. Hu et al. (2017) demonstrate in this issue of Molecular Cell that S-nitrosylation selectively modulates enzymatic activity of a protein arginine methyltransferase vital to abiotic stress tolerance.

MeSH terms

Arginine
Methylation
Protein-Arginine N-Methyltransferases*
Signal Transduction*

Substances

Arginine
Protein-Arginine N-Methyltransferases