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Nature. 1987 Feb 26-Mar 4;325(6107):783-7.

Bipolar affective disorders linked to DNA markers on chromosome 11.

Abstract

An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.

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