A polymorphic human myosin heavy chain locus is li...[Cytogenet Cell Genet. 1986]

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1: Cytogenet Cell Genet. 1986;43(1-2):117-20.Links

A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13.

Schwartz CE, McNally E, Leinwand L, Skolnick MH.

Restriction fragment length polymorphisms (RFLPs) have been developed for an adult human skeletal muscle myosin heavy chain gene which was previously mapped to the short arm of human chromosome 17. Using RFLP analysis of DNA from 140 individuals, we have found tight linkage (LOD score of 6.9) between this myosin heavy chain gene and the anonymous DNA probe, D17S1.

PMID: 2877813 [PubMed - indexed for MEDLINE]

A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436, and CRI-L329 on chromosome 14 at q11-q12. [Am J Hum Genet. 1990]
Human cardiac myosin heavy chain genes and their linkage in the genome. [Nucleic Acids Res. 1987]
Extensive DNA polymorphism at the factor XIIIa (F13A) locus and linkage to HLA. [Am J Hum Genet. 1988]
Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes. [Proc Natl Acad Sci U S A. 1984]
Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. [Science. 1983]
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A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13.

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