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Lancet. 1986 Oct 18;2(8512):877-81.

Pneumococcal vaccine prevents death from acute lower-respiratory-tract infections in Papua New Guinean children.

Abstract

In three double-blind placebo-controlled trials of pneumococcal capsular polysaccharide vaccines against death from acute lower-respiratory-tract infections (ALRI), children were vaccinated at 6 months to 5 years of age. The efficacy of the vaccines against ALRI as the sole cause of death was estimated at 59% in children vaccinated when younger than 5 years (p = 0.008) and 50% in children vaccinated when younger than 2 years (p = 0.043). Mortality from all causes was 19% less in the vaccinated group.

PMID:
2876325
[PubMed - indexed for MEDLINE]
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