Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy: A Word of Balance

J Am Coll Cardiol. 2017 Jul 25;70(4):489-494. doi: 10.1016/j.jacc.2017.06.011.

Abstract

The management of drug-refractory symptoms of obstructive hypertrophic cardiomyopathy has long been debated and is primarily centered on the choice between surgical myectomy and alcohol septal ablation. Decision making in these patients requires consideration of procedural risk, expertise and efficacy, and the long-term impact on patients' survival. Although there have been numerous reports on these procedures that may help guide decision making, these data continue to be self-reported and voluntary. Greater insight into the real-world experience for these therapies and how they should be applied in practice would be gained from mandatory reporting, akin to other multidisciplinary, transcatheter-based therapies.

Keywords: patient selection; registries; risk factors; selection bias; treatment outcome.

Publication types

  • Review

MeSH terms

  • Ablation Techniques / methods*
  • Cardiomyopathy, Hypertrophic / therapy*
  • Ethanol / pharmacology*
  • Heart Septum / drug effects*
  • Humans
  • Treatment Outcome

Substances

  • Ethanol