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    Postgrad Med J. 1986 Apr;62(726):307-8.

    Megaloblastic anaemia due to sulphasalazine responding to drug withdrawal alone.

    Grieco A, Caputo S, Bertoli A, Caradonna P, Greco AV.

    A 60 year old man with ulcerative colitis since 1975 and treated with sulphasalazine, presented with severe megaloblastic anaemia caused by folate deficiency. The drug was stopped, and the anaemia recovered promptly. There was no relapse one year later.

    PMID: 2872667 [PubMed - indexed for MEDLINE]

    PMCID: 2418663

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    Patient drug information

    • Folic Acid (Folvite®)

      Folic acid is used to treat or prevent folic acid deficiency. It is a B-complex vitamin needed by the body to manufacture red blood cells. A deficiency of this vitamin causes certain types of anemia (low red blood cell c...

    • Sulfasalazine (Azulfidine®, Azulfidine® EN-tabs®)

      Sulfasalazine is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis, a condition in which the bowel is inflamed. Sulfasalazine delayed-re...