DNA-based visual majority logic gate with one-vote veto function

Daoqing Fan; Kun Wang; Jinbo Zhu; Yong Xia; Yanchao Han; Yaqing Liu; Erkang Wang

doi:10.1039/c4sc03495c

DNA-based visual majority logic gate with one-vote veto function

Chem Sci. 2015 Mar 1;6(3):1973-1978. doi: 10.1039/c4sc03495c. Epub 2015 Jan 7.

Authors

Daoqing Fan^{1

2}, Kun Wang^{1

2

3}, Jinbo Zhu^{1

2}, Yong Xia^{1

2}, Yanchao Han^{1

2}, Yaqing Liu^{1

2}, Erkang Wang^{1

2}

Affiliations

¹ State Key Laboratory of Electroanalytical Chemistry , Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun , Jilin 130022 , P. R. China . Email: yaqingliu@ciac.ac.cn ; Email: ekwang@ciac.ac.cn.
² University of Chinese Academy of Sciences , Beijing , 100039 , China.
³ Department of Chemistry and Environmental Engineering , Changchun University of Science and Technology , Changchun , China.

Abstract

A molecular logic gate is a basic element and plays a key role in molecular computing. Herein, we have developed a label-free and enzyme-free three-input visual majority logic gate which is realized for the first time according to DNA hybridization only, without DNA replacement and enzyme catalysis. Furthermore, a one-vote veto function was integrated into the DNA-based majority logic gate, in which one input has priority over other inputs. The developed system can also implement multiple basic and cascade logic gates.