[Impact of HIV/HBV infection and HIV/HBV co-infection on outcomes of pregnancy]

Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Jun 10;38(6):837-840. doi: 10.3760/cma.j.issn.0254-6450.2017.06.029.
[Article in Chinese]

Abstract

Both HIV and HBV infection have become major health problems, of global concern, due to the high prevalence in the past few decades. Data from cumulated epidemiological surveys have shown the links between maternal HIV or HBV infection and adverse outcomes on pregnancy. Maternal HIV or HBV infection may also increase the mother-to-child (MTCT) transmission of the two diseases. However, association between HIV-HBV co-infection and adverse pregnancy is still inconclusive. Does maternal HIV-HBV co-infection have an impact on mother-to-child transmission on either HIV or HBV? Study on effective precautionary measures to promote both maternal and child's health is deemed necessary.

HIV和HBV有较高的流行率,威胁人类健康。越来越多的研究发现孕产妇HIV/HBV感染与不良妊娠之间存在联系,而且孕产妇HIV/HBV感染还会增加HIV、HBV母婴传播的风险。但目前有关这两种病毒共感染对不良妊娠结局和母婴传播的影响尚不清楚,有待进一步深入研究,为制定有效的预防措施提供科学依据,促进母婴健康。.

Keywords: Adverse pregnancy outcomes; Co-infection; HBV; HIV.

MeSH terms

  • Adult
  • Coinfection
  • Female
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV Infections / virology
  • Hepatitis B / epidemiology*
  • Hepatitis B / transmission
  • Hepatitis B / virology
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Mothers
  • Pregnancy
  • Pregnancy Complications, Infectious / virology*
  • Pregnancy Outcome / epidemiology*
  • Prevalence
  • Seroepidemiologic Studies