A study of degradation resistance and cytocompatibility of super-hydrophobic coating on magnesium

Mater Sci Eng C Mater Biol Appl. 2017 Sep 1:78:405-412. doi: 10.1016/j.msec.2017.04.057. Epub 2017 Apr 12.

Abstract

Calcium stearate based super-hydrophobic coating was deposited on plasma electrolytic oxidation (PEO) pre-treated magnesium substrate. The pre-treated magnesium and super-hydrophobic coating covered sample were characterized by scanning electron microscopy, X-ray diffraction and electrochemical corrosion measurements. The cytocompatibility and degradation resistance of magnesium, pre-treated magnesium and super-hydrophobic coating were analysed in terms of cell adhesion and osteoblast differentiation. The results indicate that the calcium stearate top coating shows super-hydrophobicity and that the surface is composed of micro/nanostructure. The super-hydrophobic coating covered sample shows higher barrier properties compared with the PEO pre-treated magnesium and bare magnesium. Human osteoblast proliferation, but not differentiation is enhanced by the PEO coating. Contrary, the super-hydrophobic coating reduces proliferation, but enhances differentiation of osteoblast, observable by the formation of hydroxyapatite. The combination of corrosion protection and cell reaction indicates that this system could be interesting for biomedical applications.

Keywords: Cytocompatibility; Degradation resistance; Magnesium; Super-hydrophobic coating.

MeSH terms

  • Alloys
  • Coated Materials, Biocompatible
  • Corrosion
  • Durapatite
  • Humans
  • Magnesium / chemistry*

Substances

  • Alloys
  • Coated Materials, Biocompatible
  • Durapatite
  • Magnesium