Adipocytes at the Core of Bone Function

Gerald Grandl; Christian Wolfrum

doi:10.1016/j.stem.2017.05.008

Adipocytes at the Core of Bone Function

Cell Stem Cell. 2017 Jun 1;20(6):739-740. doi: 10.1016/j.stem.2017.05.008.

Authors

Gerald Grandl¹, Christian Wolfrum²

Affiliations

¹ ETH Zürich, Schorenstrasse 16, CH-8603 Schwerzenbach, Switzerland.
² ETH Zürich, Schorenstrasse 16, CH-8603 Schwerzenbach, Switzerland. Electronic address: christian-wolfrum@ethz.ch.

PMID: 28575686
DOI: 10.1016/j.stem.2017.05.008

Abstract

Marrow adipose tissue (MAT) is a specialized adipose tissue with endocrine function found in bone marrow. In this issue of Cell Stem Cell, Ambrosi et al. (2017) identify a stem cell population in the bone marrow that can give rise to both osteogenic and adipogenic MAT precursors and is regulated by diet and aging and affects bone functionality.

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MeSH terms

Adipocytes
Adipose Tissue
Bone Marrow*
Bone Regeneration
Hematopoietic Stem Cell Transplantation*
Humans
Obesity