Management of Metastatic Gastric Cancer

Hematol Oncol Clin North Am. 2017 Jun;31(3):469-483. doi: 10.1016/j.hoc.2017.01.006. Epub 2017 Mar 22.

Abstract

Metastatic gastric cancer is an incurable disease. Systemic chemotherapy prolongs survival, improves symptom control, and helps maintain a better quality of life of patients with metastatic gastric cancer. HER2 testing of the primary tumor and/or the metastases is warranted before initiation of first-line treatment. This review article outlines the indication and clinical data of medical treatment of advanced gastric cancer and highlights aspects of quality of life.

Keywords: Chemotherapy; Doublet; Gastric cancer; Metastases; Radiotherapy; Sequence; Surgery; Triplet.

Publication types

  • Review

MeSH terms

  • Disease-Free Survival
  • Humans
  • Neoplasm Metastasis
  • Quality of Life
  • Receptor, ErbB-2* / genetics
  • Receptor, ErbB-2* / metabolism
  • Stomach Neoplasms* / genetics
  • Stomach Neoplasms* / metabolism
  • Stomach Neoplasms* / mortality
  • Stomach Neoplasms* / therapy
  • Survival Rate

Substances

  • ERBB2 protein, human
  • Receptor, ErbB-2