What is known and objective: The impact of gastric bypass surgery on the pharmacokinetics of various medications has been reported. Presently, no data exist for the treatment of chronic hepatitis C virus with ledipasvir/sofosbuvir (LDV/SOF) in an individual with a history of gastric bypass.
Case description: We report the successful cure of an individual who was treated with LDV/SOF who had a history of gastric bypass. The patient tolerated LDV/SOF well while only experiencing a minor headache.
What is new and conclusion: Ledipasvir/sofosbuvir treatment may still be effective in those with a history of gastric bypass surgery.
Keywords: LDV/SOF; harvoni; hepatitis C virus; ledipasvir/sofosbuvir.
© 2017 John Wiley & Sons Ltd.