Reference standards for lean mass measures using GE dual energy x-ray absorptiometry in Caucasian adults

PLoS One. 2017 Apr 20;12(4):e0176161. doi: 10.1371/journal.pone.0176161. eCollection 2017.

Abstract

Objective: To develop reference values by age and sex for LM measures using GE-Healthcare DXA systems.

Methods: A de-identified sample was obtained from Ball State University's Clinical Exercise Physiology Laboratory and University of Wisconsin-Milwaukee's Physical Activity & Health Research Laboratory. DXA scans of 2,076 women and 1,251 men were completed using a GE Lunar Prodigy or iDXA. Percentiles (%ile) were calculated for all variables of interest (LM, LMI, %LM, and ALMI) and a factorial ANOVA was used to assess differences for each variable between 10-year age groups and sex, as well as the interaction between age and sex.

Results: Men had higher mean total LM, %LM, LMI, and ALMI than women (p<0.01), across all age groups. All LM variables decreased significantly over the 5 decades in men, however in women only total LM, %LM, and ALMI decreased from the youngest to oldest age groups (p<0.01).

Conclusion: These reference values provide for a more accurate interpretation of GE-Healthcare DXA-derived LM measurements offering clinicians and researchers with an initial resource to aid in the early detection and assessment of LM deficits.

MeSH terms

  • Absorptiometry, Photon
  • Adult
  • Aged
  • Body Composition*
  • Female
  • Humans
  • Male
  • Muscle, Skeletal / diagnostic imaging*
  • Reference Standards
  • White People*
  • Young Adult

Grants and funding

The authors received no specific funding for this work.