Abstract
Phytochemical studies on the stem bark of Garcinia nervosa has resulted in the discovery of one new pyranoxanthone derivative, garner xanthone (1) and five other compounds, 1,5-dihydroxyxanthone (2), 6-deoxyisojacareubin (3), 12b-hydroxy-des-D-garcigerrin A (4) stigmasterol (5), and β-sitosterol (6). The structures of these compounds were elucidated with the aid of spectroscopic techniques, such as NMR and MS. The crude extracts of the plant were assessed for their antimicrobial activity.
Keywords:
Clusiaceae; Garcinia nervosa; antimicrobial; xanthones.
MeSH terms
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Anti-Infective Agents / pharmacology*
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Drug Evaluation, Preclinical / methods
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Garcinia / chemistry*
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Molecular Structure
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Plant Bark / chemistry
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Pyrans / chemistry
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Pyrans / isolation & purification
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Sitosterols / chemistry
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Sitosterols / isolation & purification
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Stigmasterol / chemistry
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Xanthenes / chemistry
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Xanthenes / isolation & purification
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Xanthones / chemistry
Substances
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6-deoxyisojacareubin
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Anti-Infective Agents
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Pyrans
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Sitosterols
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Xanthenes
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Xanthones
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garner xanthone
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gamma-sitosterol
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xanthone
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Stigmasterol