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Department of Pathology, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston 77030.
A case of mucin-secreting renal cell carcinoma in a 65-year-old man is presented. Both luminal and cytoplasmic mucin was present as demonstrated by Mayer's mucicarmine and alcian blue stains at a pH of 0.9 and 2.5, respectively. In a control series of 18 consecutive renal cell carcinomas, only focal luminal staining with alcian blue at a pH of 2.5 was demonstrated in two cases. Neither cytoplasmic staining for alcian blue nor luminal or cytoplasmic reactivity with mucicarmine was present. The presence of mucin in a tumor does not exclude a possible renal origin.
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