Despite advances in medical care, mortality due to cerebral Nocardia abscesses remains unacceptably high. The case of a typical immunocompromised patient, who deteriorated clinically despite optimal antimicrobial treatment, is reported here. Adjuvant immunotherapy with interferon-gamma resulted in partial restoration of the immune response and a corresponding clinical and radiographic recovery.
Keywords: Cerebral abscess; IFN-gamma; Immunotherapy; Nocardia; Nocardiosis.
Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.