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    FEBS Lett. 1988 Feb 8;228(1):153-6.

    Isolation of human pancreastatin fragment containing the active sequence from a glucagonoma.

    Sekiya K, Ghatei MA, Minamino N, Bretherton-Watt D, Matsuo H, Bloom SR.

    Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, England.

    Erratum in:

    • FEBS Lett 1988 Apr 25;231(2):451.

    The primary structure of a human pancreastatin-like peptide was determined from a pancreatic glucagonoma. The 28-amino acid peptide was identified using a specific antibody raised against porcine pancreastatin 1-49 and showed a 75% sequence homology with porcine pancreastatin 22-49 and bovine chromogranin A 267-294. Several forms of pancreastatin-like immunoreactivity were found in human endocrine tumors of which the purified peptide was the smallest and contained the active sequence of pancreastatin.

    PMID: 2830133 [PubMed - indexed for MEDLINE]

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