Depression, anxiety and health-related quality of life amongst patients who are starting dialysis treatment

J Ren Care. 2017 Jun;43(2):73-82. doi: 10.1111/jorc.12195. Epub 2017 Feb 27.

Abstract

Background: Chronic kidney disease (CKD) has a severe impact on patients' health-related quality of life (HRQL). The start of renal replacement therapy (RRT) significantly influences psychological, physical and social aspects of life.

Objectives: To analyse the HRQL and psychological status (anxiety and depression) at the start of RRT.

Methods: We undertook an observational descriptive cross-sectional study. A total of 152 patients starting RRT were recruited for the study. HRQL was measured by the Kidney Disease and Quality of Life Short Form questionnaire. Levels of anxiety and depression were assessed by the Hospital Anxiety and Depression Scale questionnaire. Comorbidities and sociodemographic and clinical factors were also evaluated.

Findings: HRQL in patients with end-stage kidney disease (ESKD) is significantly affected by the initiation of RRT in all respects. States of anxiety and depression were present in 26.6% and 27% of patients, respectively. These states are significantly related to the emotional component of the quality of life.

Conclusion: The initiation of RRT has a strong impact on HRQL in comparison with a reference population and with other stages of CKD. The early detection of an altered psychological state is important, as this condition should be treated from the first stages of the disease, as it can significantly affect the subsequent development of RRT and the patient's quality of life.

Keywords: Anxiety; Depression; End-stage kidney disease; Health-related quality of life; Renal replacement therapy.

MeSH terms

  • Aged
  • Anxiety / psychology*
  • Depression / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychometrics / instrumentation
  • Psychometrics / methods
  • Quality of Life / psychology*
  • Renal Dialysis / adverse effects
  • Renal Insufficiency, Chronic / complications
  • Renal Insufficiency, Chronic / psychology*
  • Renal Replacement Therapy / adverse effects
  • Renal Replacement Therapy / psychology*
  • Surveys and Questionnaires