IL-27: a new target for GVHD prevention

Blood. 2016 Oct 20;128(16):2003-2004. doi: 10.1182/blood-2016-08-732974.

Abstract

In this issue of Blood, Belle et al have identified a key role for interleukin-27 (IL-27) in acute graft-versus-host disease (GVHD), which is a complex process orchestrated by donor immune T cells and antigen-presenting cells of both donor and host origin.

Publication types

  • Comment

MeSH terms

  • Bone Marrow Transplantation
  • Graft vs Host Disease / prevention & control*
  • Humans
  • Interleukin-27*

Substances

  • Interleukin-27