Send to

Choose Destination
See comment in PubMed Commons below
Psychopharmacology (Berl). 1989;99 Suppl:S64-7.

Predictors of response to clozapine therapy.

Author information

  • 1Sandoz Research Institute, East Hanover, NJ 07936.


Multiple regression analysis and discriminant function analyses were applied to the question of prediction of therapeutic success or failure to clozapine therapy, using a non-biological predictor pool of 46 items. This effort was not successful, accounting for less than 25% of outcome variance under optimal conditions. However, it does appear that while clozapine efficacy in treatment-resistant schizophrenic patients in general is superior to such neuroleptics as chlorpromazine or haloperidol, the "paranoid" subgroup appears to benefit most.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk