[Incidence of bacteria from cultures of bile and gallbladder wall of laparoscopic cholecystectomy patients in the University Hospital "Dr. José Eleuterio González"]

Cir Cir. 2017 Nov-Dec;85(6):515-521. doi: 10.1016/j.circir.2016.10.030. Epub 2017 Jan 16.
[Article in Spanish]

Abstract

Background: Through experience it has been accepted that bile in normal conditions remains sterile. Bactibilia is a common finding in individuals at high risk or with complicated cholecystolithiasis, however few data prevails about the prevalence of bactibilia in patients operated on for uncomplicated laparoscopic cholecystectomy. There is s common usage of preoperative and postoperative antibiotics in the different patients without the existence of any actual bacteriologic and epidemiologic evidence.

Material and methods: 183 patients with diagnosis of cholecystolithiasis postoperated of laparoscopic cholecystectomy had their bile sent to bacteriology.

Results: Bactibilia was identified in 31.95% of the cultures of mild cholecystitis and in 35.71% for moderate (p<.0001). A total of 125 negative cultures were obtained (68.3) and 58 positive (31.69%) with a prevalence of enterobacteria group (43.10%) and Enterococcus (27.58).

Conclusions: Comparing the groups according to severity there is a significant difference with regard to the presence of bactibilia, in addition to the bacterial groups cultivated. Fluoroquinolones and metronidazole is an option for the treatment of patients with the suspicion of bactibilia. The use of antibiotics is not justified in patients at low risk.

Keywords: Antibioticoterapia; Bactibilia; Colecistectomía laparoscópica; Laparoscopic cholecystectomy; Treatment with antibiotics.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Bacteriological Techniques
  • Bile / microbiology*
  • Cholecystectomy, Laparoscopic*
  • Cholecystitis / microbiology*
  • Cholecystitis / surgery
  • Cholelithiasis / microbiology*
  • Cholelithiasis / surgery
  • Cross-Sectional Studies
  • Drug Resistance, Microbial
  • Enterobacteriaceae / isolation & purification*
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / microbiology*
  • Enterococcus / isolation & purification*
  • Female
  • Gallbladder / microbiology*
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / microbiology*
  • Hospitals, University
  • Humans
  • Incidence
  • Male
  • Middle Aged

Substances

  • Anti-Bacterial Agents