Crystal structure of 1-[2-(4-chloro-phen-yl)-4,5-diphenyl-1 H-imidazol-1-yl]propan-2-ol

Shaaban K Mohamed; Adel A Marzouk; Mustafa R Albayati; Antar A Abdelhamid; Jim Simpson

doi:10.1107/S2056989016019332

Crystal structure of 1-[2-(4-chloro-phen-yl)-4,5-diphenyl-1 H-imidazol-1-yl]propan-2-ol

Acta Crystallogr E Crystallogr Commun. 2017 Jan 1;73(Pt 1):59-62. doi: 10.1107/S2056989016019332.

Authors

Shaaban K Mohamed¹, Adel A Marzouk², Mustafa R Albayati³, Antar A Abdelhamid⁴, Jim Simpson⁵

Affiliations

¹ Faculty of Science and Engineering, Health Care Division, Manchester Metropolitan University, Manchester M1 5GD, England; Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.
² Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al Azhar University, 71515 Assiut, Egypt.
³ Kirkuk University, College of Education, Department of Chemistry, Kirkuk, Iraq.
⁴ Chemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
⁵ Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.

Abstract

The title compound, C₂₄H₂₁ClN₂O, crystallizes with two unique mol-ecules in the asymmetric unit. In each mol-ecule, the central imidazole ring is substituted at the 2-, 4- and 5-positions by benzene rings. The 2-substituted ring carries a Cl atom at the 4-position. One of the imidazole N atoms in each mol-ecule has a propan-2-ol substituent. In the crystal, a series of O-H⋯N, C-H⋯O and C-H⋯Cl hydrogen bonds, augmented by several C-H⋯π(ring) inter-actions, generate a three-dimensional network of mol-ecules stacked along the a-axis direction.

Keywords: C—H⋯π interactions; crystal structure; hydrogen bonding; multi-substituted imidazole.