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Explosive eruption of pyogenic granuloma on the scalp due to topical combination therapy of minoxidil and retinoic acid.
Dermatologic Division, Centre Hospitalier, Cannes, France.
A 55-year-old patient was treated with a combination of minoxidil and retinoic acid. After 1 month an explosive eruption of pyogenic granuloma appeared on the scalp. Despite redness and itchy reaction, caused only by the test containing both chemicals, histology did not give evidence of contact allergy.
PMID: 2792494 [PubMed - indexed for MEDLINE]
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Patient Drug Information
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Tretinoin (Vesanoid® )
Tretinoin is used to treat acute promyelocytic leukemia (APL; a type of cancer in which there are too many immature blood cells in the blood and bone marrow) in people who have not been helped by other types of chemother...
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Tretinoin Topical (Avita® , Renova® Emollient, Retin-A® , ...)
Tretinoin is used to treat acne. It promotes peeling of affected skin areas and unclogs pores. Tretinoin controls acne but does not cure it.
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Minoxidil Topical (Rogaine® )
Minoxidil is used to stimulate hair growth and to slow balding. It is most effective for people under 40 years of age whose hair loss is recent. Minoxidil has no effect on receding hairlines. It does not cure baldness; m...