Liver Segmentation on CT and MR Using Laplacian Mesh Optimization

IEEE Trans Biomed Eng. 2017 Sep;64(9):2110-2121. doi: 10.1109/TBME.2016.2631139. Epub 2016 Nov 21.

Abstract

Objective: The purpose of this paper is to describe a semiautomated segmentation method for the liver and evaluate its performance on CT-scan and MR images.

Methods: First, an approximate 3-D model of the liver is initialized from a few user-generated contours to globally outline the liver shape. The model is then automatically deformed by a Laplacian mesh optimization scheme until it precisely delineates the patient's liver. A correction tool was implemented to allow the user to improve the segmentation until satisfaction.

Results: The proposed method was tested against 30 CT-scans from the SLIVER07 challenge repository and 20 MR studies from the Montreal University Hospital Center, covering a wide spectrum of liver morphologies and pathologies. The average volumetric overlap error was 5.1% for CT and 7.6% for MRI and the average segmentation time was 6 min.

Conclusion: The obtained results show that the proposed method is efficient, reliable, and could effectively be used routinely in the clinical setting.

Significance: The proposed approach can alleviate the cumbersome and tedious process of slice-wise segmentation required for precise hepatic volumetry, virtual surgery, and treatment planning.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Algorithms*
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Liver / diagnostic imaging*
  • Machine Learning
  • Magnetic Resonance Imaging / methods*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*
  • User-Computer Interface