Format

Send to:

Choose Destination
See comment in PubMed Commons below
Acta Cytol. 1989 May-Jun;33(3):359-62.

Fine needle aspiration cytology and immunocytochemistry of large cell lymphomas expressing the Ki-1 antigen.

Author information

  • 1Department of Pathology, Karolinska Hospital, Stockholm, Sweden.

Abstract

Cytomorphology and immunocytochemistry were used to diagnose two cases of large cell anaplastic lymphomas that expressed the Ki-1 antigen. Smears stained with the May-Grünwald-Giemsa stain showed a cytomorphologic spectrum that varied from immunoblastlike cells to large tumor cells with pleomorphic nuclei. The tumor cells had a distinct basophilic cytoplasm, which often contained vacuoles. Giant cells with wreathlike multilobulated bizarre nuclei were also observed. Immunocytochemistry on a cytocentrifuged specimen showed that the tumor cells were of a T-helper phenotype; all strongly expressed the Ki-1 antigen and receptors for HLA-DR and IL-2.

PMID:
2786306
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk