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Science. 1989 Sep 22;245(4924):1351-7.

Contragestion and other clinical applications of RU 486, an antiprogesterone at the receptor.

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  • 1INSERM U 33 (Communications hormonales), Faculté de Médicine, Université Paris-Sud, Bicêtre, France.

Abstract

RU 486, a steroid with high affinity for the progesterone receptor, is the first available active antiprogesterone. It has been used successfully as a medical alternative for early pregnancy interruption, and it also has other potential applications in medicine and for biochemical and pathophysiological endocrine research.

PMID:
2781282
[PubMed - indexed for MEDLINE]
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