J Nat Prod. 1989 May-Jun;52(3):629-33.

Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin.

Van Puyvelde L, De Kimpe N, Costa J, Munyjabo V, Nyirankuliza S, Hakizamungu E, Schamp N.

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Centre Universitaire de Recherche sur la Pharmacopée et la Médecine Traditionnelle, Université Nationale du Rwanda, Butare.

Abstract

3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of the mp of the latter chalcone, a synthesis of helichrysetin was developed. 3-O-Methylquercetin was shown to be an active principle as it displayed antimicrobial activity.

PMID:: 2778452; [PubMed - indexed for MEDLINE]

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Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin.

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