Near-infrared multispectral photoacoustic microscopy using a graded-index fiber amplifier

Takashi Buma; Jessica L Farland; Margaret R Ferrari

doi:10.1016/j.pacs.2016.08.002

Near-infrared multispectral photoacoustic microscopy using a graded-index fiber amplifier

Photoacoustics. 2016 Aug 16;4(3):83-90. doi: 10.1016/j.pacs.2016.08.002. eCollection 2016 Sep.

Authors

Takashi Buma¹, Jessica L Farland², Margaret R Ferrari²

Affiliations

¹ Department of Electrical and Computer Engineering, Union College, Schenectady, NY 12308, USA; Bioengineering Program, Union College, Schenectady, NY 12308, USA.
² Bioengineering Program, Union College, Schenectady, NY 12308, USA.

Abstract

We demonstrate optical resolution photoacoustic microscopy (OR-PAM) of lipid-rich tissue using a multi-wavelength pulsed laser based on nonlinear fiber optics. 1047 nm laser pulses are converted to 1098, 1153, 1215, and 1270 nm pulses via stimulated Raman scattering in a graded-index multimode fiber. Multispectral PAM of a lipid phantom is demonstrated with our low-cost and simple technique.

Keywords: Graded-index multimode fiber; Photoacoustic microscopy; Stimulated Raman scattering.